Publications by authors named "K Ayabe"
Landiolol, an ultra-short-acting β1-selective blocker, is more effective in controlling heart rate compared with digoxin in patients with atrial tachyarrhythmias and left ventricular dysfunction. However, the effect of atrial tachyarrhythmia type on the effectiveness of landiolol remains unknown. Hence, this study aimed to evaluate the effectiveness of landiolol in patients with atrial fibrillation (AF) and atrial tachycardia (AT), not limited to those with heart failure with a reduced ejection fraction.
View Article and Find Full Text PDFClinical relevance of left atrial structural remodeling and non-pulmonary vein foci in atrial fibrillation.
J Interv Card Electrophysiol
October 2024
Background: The mechanistic role of left atrial (LA) structural remodeling as a non-pulmonary vein (PV) trigger in the initiation of atrial fibrillation (AF) remains uncertain. This study is aimed at prospectively evaluating the association between non-PV triggers and LA structural remodeling.
Methods: A total of 517 patients undergoing catheter ablation for AF were included.
Article Synopsis
- Bone morphogenetic proteins (BMPs) play a key role in the development and differentiation of bone and cartilage, particularly through their interactions with specific receptors on cells.
- In mouse chondrocyte precursor cells (ATDC5), the protein MSK1 is rapidly activated by BMP-6 stimulation, influencing the differentiation processes when either overexpressed or suppressed.
- The study highlights the involvement of both p38 kinase pathways and Smad proteins in BMP-6-induced chondrocyte differentiation, indicating that MSK1 activation is essential for these processes.
Background: Atrial fibrillation (AF) and coronary artery disease (CAD) often co-occur. The prevalence of coincident AF and CAD, the characteristics of such patients, and the correlation with thromboembolic risk in association with renal function are unclear.
Methods And Results: We studied 435 consecutive patients who underwent contrast-enhanced computed tomography (CT) before catheter ablation for AF.
Background: Open-window mapping (OWM) is a novel automated mapping method for catheter ablation of an accessory pathway (AP), in which the local signal is annotated with window-of-interest parameters to analyze both atrial and ventricular signals. This study aimed to determine the utility of OWM in visualizing the location and width of APs in patients with Wolff-Parkinson-White syndrome.
Methods: This two-center study enrolled 30 patients (20 males; mean age: 56 years, interquartile range [IQR]: 22-69 years) who underwent high-density OWM with the extended early-meets-late (EEML) algorithm using a 20-electrode, 5-spline catheter (PENTARAY, Biosense Webster).