Pathologically different features and fibrosis scores in chronic hepatitis C genotypes 3 and 1.

Background: Chronic hepatitis C genotypes 3 and 1 are the two most common genotypes in Thailand.

Objective: Identify the pathologically different features between genotypes 3 and land to compare the fibrosis score of Knodell HAI and Ishak modified HAI.

Material And Method: The pathological features of 114 liver biopsies were evaluated.

Vanishing bile duct syndrome in a child with toxic epidermal necrolysis: an interplay of unbalanced immune regulatory mechanisms.

Vanishing bile duct syndrome (VBDS) is a rare disorder and requires a liver biopsy for a diagnosis. The condition has not been reported in children with toxic epidermal necrolysis (TEN). The etiology of VBDS in our patient with TEN is most likely from drug hypersensitivity.

A rapid serologic test and immunoblotting for the detection of Helicobacter pylori infection in children.

The gold standard for the diagnosis of Helicobacter pylori infection requires an endoscopic biopsy of gastric mucosa for histological examination, urease test and culture. Noninvasive serological tests are useful as a screening test for H. pylori infection.

Factors predisposing to peptic ulcer disease in asymptomatic cirrhotic patients.

Background: There is a high prevalence of peptic ulcer in cirrhotic patients, but the pathogenesis of peptic ulcer in cirrhosis remains inconclusive.

Aim: To investigate factors associated with peptic ulcer and to evaluate peptic ulcer prevalence in asymptomatic cirrhotic patients.

Methods: A total of 130 cirrhotics were recruited into the study for endoscopic screening.