Publications by authors named "K Anastos"
This study examined the association between cognitive intra-individual variability (IIV), a non-mean-based indicator of underlying neuropathology, and self-reported everyday functioning of 1,086 women with HIV (WWH) and 494 socio-demographically similar women without HIV (WWoH). Objective cognitive performance across seven domains and the self-rated Lawton & Brody scale of Instrumental Activities of Daily Living (IADL) were assessed among participants of the Women's Interagency HIV Study. Two types of cognitive IIV were calculated by taking the standard deviation across seven cognitive domains to calculate dispersion: 1) intra-individual standard deviation (denoted as IIV) and 2) coefficient of variation (denoted as IIV).
View Article and Find Full Text PDFWe studied cervicovaginal β-/γ-human papillomavirus (HPV) and their relationship to cervical precancer in women with HIV (WWH); having previously reported strong positive associations of β-/γ-HPV with incident head and neck cancer in the general population. Cases (N=124) had cervical intraepithelial neoplasia (CIN)-3 or CIN-2. Controls (N=247) were individually matched 2:1 to cases.
View Article and Find Full Text PDFArticle Synopsis
- The study focused on PrEP retention rates among key populations at high HIV risk in Rwanda, specifically female sex workers (FSWs) and men who have sex with men (MSM), highlighting disparities in retention at 1 and 12 months after starting PrEP treatment.* -
- Results showed that 92% of participants were retained at 1 month and 77% at 12 months, with retention influenced by factors such as living situations and perceived HIV risk, particularly among FSWs, while MSM retention was affected by education and employment status.* -
- The findings underline the need for targeted interventions to improve PrEP retention, particularly among groups with lower education levels or different employment statuses, to ensure ongoing HIV prevention support.*
Article Synopsis
- Head and neck cancer (HNC) is a growing health issue in Rwanda, with a study analyzing data from 1001 patients revealing that 82% had squamous cell carcinoma and a mean age of diagnosis at 51.1 years, predominantly in males.
- The study utilized p16 immunohistochemistry to assess HPV prevalence, finding that 22% of cases were p16-positive, with 19% testing positive for HPV, particularly HPV16.
- It concluded that there is an urgent need for improved cancer testing and data collection in Rwanda to better understand and combat HNC, especially focusing on oropharyngeal cases and associated risk factors.
Article Synopsis
- The study investigates racial disparities in SARS-CoV-2 vaccination rates among people with HIV (PWH) and those at risk for HIV, focusing on the roles of medical mistrust and vaccine hesitancy.
- It utilizes data from a diverse cohort and employs various statistical analyses to explore the impact of social demographics on vaccination attitudes and behaviors.
- Results show that Black participants are significantly more likely to be unvaccinated compared to white participants, primarily due to medical mistrust and vaccine hesitancy, highlighting the urgent need for improving trust in healthcare to address these disparities.