Publications by authors named "K Al-Kattan"

Purpose: The primary objective of this study was to assess the various coping strategies that medical students at Alfaisal College of Medicine use to adapt to stressors and adversities faced in a medical school environment.

Methods: This cross-sectional study utilized an online questionnaire distributed to medical students (aged 18+) at Alfaisal University from March 15 to April 30, 2023. Inclusion criteria focused on College of Medicine students from Years 1 to 5.

View Article and Find Full Text PDF
Article Synopsis
  • * Early detection is crucial but challenging because symptoms can be minimal or non-specific, and traditional screening methods like imaging and biopsy have limitations in accuracy, cost, and invasiveness.
  • * Innovative biosensors are emerging as a rapid, cost-effective, and less invasive alternative for detecting HCC by identifying various biomarkers, showing promise for improved early diagnosis compared to conventional methods.
View Article and Find Full Text PDF

Exosomal microRNAs (miRNAs) have great potential in the fight against hepatocellular carcinoma (HCC), the fourth most common cause of cancer-related death worldwide. In this study, we explored the various applications of these small molecules while analyzing their complex roles in tumor development, metastasis, and changes in the tumor microenvironment. We also discussed the complex interactions that exist between exosomal miRNAs and other non-coding RNAs such as circular RNAs, and show how these interactions coordinate important biochemical pathways that propel the development of HCC.

View Article and Find Full Text PDF

Hepatocellular carcinoma (HCC) is currently one of the most prevalent cancers worldwide. Associated risk factors include, but are not limited to, cirrhosis and underlying liver diseases, including chronic hepatitis B or C infections, excessive alcohol consumption, nonalcoholic fatty liver disease (NAFLD), and exposure to chemical carcinogens. It is crucial to detect this disease early on before it metastasizes to adjoining parts of the body, worsening the prognosis.

View Article and Find Full Text PDF