Publications by authors named "K Akpir"
Background: Mechanical ventilation with high peak inspiratory pressure (PIP) induces lung injury and bacterial translocation from the lung into the systemic circulation. We investigated the effects of increased inspiratory time on translocation of intratracheally inoculated bacteria during mechanical ventilation with and without extrinsic positive end-expiratory pressure (PEEP).
Methods: Rats were ventilated in pressure-controlled mode with 14 cm H2O PIP, 0 cm H2O PEEP, I:E ratio 1/2, and Fio2 1.
Background: In this prospective, clinical study we tested the hypothesis whether two different doses of spinal administered bupivacaine and accordingly, two different levels of spinal anaesthesia can affect the dose requirement of propofol during BIS guided sedation.
Methods: Fifty women undergoing vaginal hysterectomy (high spinal group, HS) or transvaginal tape (TVT) procedure for urinary incontinence (low spinal group, LS) under spinal anaesthesia were enrolled to the study. In group HS, 17.
The success rate of cardiopulmonary resuscitation (CPR) may differ from institution to institution, even within different sites in the same institution. A variety of factors may influence the outcome. In this study, we assessed the adequacy of CPR attempts guided by the current standards and aimed to define the factors influencing the outcome following in-hospital cardiac arrest.
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- The study examined the impact of three magnesium dosing regimens on anesthesia and pain management in women undergoing gynaecological surgery.
- Magnesium groups required significantly less propofol and atracurium compared to the control group, leading to lowered morphine use post-surgery.
- The findings suggest that a magnesium bolus followed by a lower continuous infusion reduces the need for anesthetics without additional benefits from higher doses, while also affecting heart rates.
Objective: To evaluate the time course of Pao2 change following the setting of optimal positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome (ARDS).
Design: Prospective clinical study.
Setting: Multidisciplinary intensive care unit of a university hospital.