Publications by authors named "K Akieda"

Background: Acrylamide poisoning is often reported as chronic poisoning presenting with peripheral neuropathy or carcinogenic action due to long-term exposure to low concentrations. However, there have been few reports of acute poisoning due to oral ingestion of acrylamide, where the symptoms appear a few hours after ingestion. Here, we report a case of acute acrylamide poisoning where a high concentration was ingested in a short time, resulting in a fatal outcome due to the rapid course of events.

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Background: The primary purpose of this study was to investigate risk factors associated with the need for mechanical ventilation (MV) and extracorporeal membrane oxygenation (ECMO) in COVID-19 patients admitted to the intensive care unit (ICU).

Methods: We retrospectively enrolled 66 consecutive COVID-19 patients admitted to the ICUs of three Japanese institutions from February 2020 to January 2021. We performed logistic regression analyses to identify risk factors associated with subsequent MV and ECMO requirements.

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Article Synopsis
  • Sepsis is a leading cause of death in ICUs and contributes to long-term physical, cognitive, and mental health problems (collectively known as post-intensive care syndrome, or PICS) for both patients and their families.
  • A multicenter study across 26 ICUs will follow patients over five years after their ICU stay to analyze the effectiveness of the ABCDEF care bundle on survival rates and the incidence of PICS.
  • The study has received ethical approvals, and findings will be shared in peer-reviewed journals and at scientific conferences, ensuring transparency and dissemination of results.
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Objective: To determine whether antithrombotic therapy with warfarin is effective and safe in patients who developed venous thromboembolism in the acute stage of polytrauma, which is associated with bleeding risk.

Method: A retrospective study of 11 patients (8 males, 3 females; mean age, 39.8 years; injury severity score, 30.

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