Predictive Factors for the Necessity of Hospitalization of Patients With Acute Alcohol Intoxication.

Background: The aim of the study was to identify factors related to the need for hospitalization due to acute alcohol intoxication.

Methods: The data of 42 patients with acute alcohol intoxication who visited our hospital from April 1, 2014 to September 30, 2015 were available for analysis. Factors related to outcome included hospitalization or release to home, Glasgow coma scale (GCS), temperature, pulse rate, blood pressure, oxygen saturation of the peripheral artery (SpO), and respiratory rate.

A case of transient global amnesia with hippocampal infarction due to infective endocarditis.

Transient global amnesia (TGA) is an uncommon disease characterized by sudden onset anterograde amnesia that typically improves within 24 hours. A 35-year-old woman presented with complete disruption of memory that had started on the previous day. She had fever and heart murmur and was diagnosed as having infective endocarditis with Staphylococcus lugdunensis, a coagulase-negative staphylococcus.

Synthesis of 5a,5a'-dicarba-d-glucobioses from conformationally restricted carbaglucosyl triflates using S2-type inversion with carbaglucosyl nucleophiles.

Novel carbohydrate mimics were designed which contain two 5a-carba-d-glucose residues, one each at reducing and nonreducing end, and thus these mimics are 5a,5a'-dicarba-d-glucobioses. Dicarbadisaccharides have attractive features such as stability against endogenous degradative enzymes and being resistant to glycation reactions such as the Maillard reaction. For the synthesis of dicarba-β-d-isomaltose derivatives, the carbaglucosyl triflate locked in C conformation was synthesized by protecting with butane-2,3-diacetal group or benzylidene group.

Maoto, a Traditional Japanese Herbal Medicine, Inhibits Uncoating of Influenza Virus.

We previously reported in randomized controlled trials that maoto, a traditional herbal medicine, showed clinical and virological efficacy for seasonal influenza. In this study, a culturing system for influenza was used to test the effect of maoto. A549 cells in the culture were infected with influenza virus A (PR8) and followed after treatment with maoto; the virus titers in the culture supernatant, intracellular viral proteins, and viral RNA were determined.

Structural Characteristics and Antioxidant Activities of Fucoidans from Five Brown Seaweeds.

Five kinds of fucoidans from the brown seaweeds , , (), , and , were isolated according to a previously reported procedure with slight modification. The scavenging activities of DPPH radical, superoxide radical, and hydroxyl radical, as well as the ORAC value were measured for the isolated fucoidans. Fucoidans from , , and showed higher antioxidant activity than that from and , except for the hydroxyl radical scavenging activity.