Publications by authors named "K Adel-Patient"
Background: Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated allergy without known biomarkers. We aimed to compare fecal biomarkers related to gut inflammation and immunity in children with FPIES, with resolved FPIES (tolerant), and in matched controls.
Methods: Stools were collected from FPIES children on elimination diet, before and after an oral food challenge (OFC) performed to assess their natural tolerance, at the end of a follow-up in tolerant FPIES children, and in matched controls (1:1 ratio).
Exposure to environmental chemicals has been associated with higher risk of childhood allergies. This study aimed to examine the association between infant's dietary exposure to mixtures of chemicals and allergic and respiratory multimorbidity in childhood. Dietary exposures were assessed at 8 and 12 months in 724 and 745 children of the EDEN cohort.
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- A study investigated how the antioxidant capacity and inflammation potential of maternal diets during the last three months of pregnancy could influence the risk of allergic and respiratory diseases in children.
- Researchers analyzed data from 9,679 mother-child pairs, measuring the dietary antioxidant capacity and inflammatory potential using various indices.
- Results indicated that a diet high in antioxidants was linked to a lower risk of 'early wheeze without asthma,' while a pro-inflammatory diet correlated with a higher risk of 'asthma only,' suggesting maternal diet impacts children's respiratory health to some extent.
New dietary trends and alternative proteins: the emergence of novel food allergens.
Curr Opin Clin Nutr Metab Care
January 2025
Purpose Of Review: New dietary trends driven by environmental and health considerations will undoubtedly lead to the emergence of novel food allergens. Assessment of the allergenic risk of new or modified protein-containing food sources and ingredients, as well as surveillance of emerging food allergies, is then required.
Recent Findings: Developments of in silico and in vitro models apprehending protein capacity to cross-react with other homologous proteins and to induce a de novo allergic sensitization are ongoing to better integrate multiple parameters such as 3D structural information or major histocompatibility complex class II (MHC-II) presentation propensity.
Article Synopsis
- The study investigates how maternal diet during pregnancy affects exposure to toxic trace elements like arsenic, mercury, and lead.
- It found that women with healthier dietary patterns had higher levels of arsenic and mercury in their bodies, while lead levels in cord blood were less directly linked to diet.
- Interestingly, a Western dietary pattern was connected to lower mercury levels, suggesting that not all "healthy" foods are equal when it comes to toxic exposure during pregnancy.