Citrus pectins impact the function of chicken macrophages.

The restrictions on excessive use of antimicrobials in the poultry industry have led to the search for alternative strategies including nutritional interventions to enhance gut health with the ultimate aim to prevent gut infections. Pectins as prebiotics have shown beneficial effects on gut health in humans and mice by improving the gut barrier function, altering the gut microbiota, and by modulating the gut immune response. However, little is known about immunomodulatory properties of pectins in chickens.

Effect of direct oral anticoagulants compared to enoxaparin on objective response to immune checkpoint inhibitors in patients with lung cancer.

Introduction: A hypoxic tumor microenvironment inhibits the normal functioning of immune cells. Studies have hypothesized that anticoagulants that can penetrate and bind to factor Xa in the tumor microenvironment, can enhance T-cell function and augment immunotherapy activity. This study compared objective response rate and progression-free survival of lung cancer patients on concomitant immunotherapy treated with direct-acting oral anticoagulants versus enoxaparin.

A Cross-Sectional Study Revealed a Low Prevalence of SARS-CoV-2 Infection among Asymptomatic University Students in Tripoli, North Lebanon.

This study aimed to investigate the SARS-CoV-2 infection prevalence among >18-year-old students in the Faculty of Public Health and Faculty of Sciences at the Lebanese University in Tripoli, Northern Lebanon, in June 2023 and to characterize the circulating Omicron subvariants. Out of 357 participants, only 2 (0.56%) tested positive by qPCR, corresponding to 0.

Dinuclear Cobalt(II) Bis-Dipyrromethane Complexes: Synthesis via Divergent Transmetalation Reactions.

A bis-dipyrromethane ligand, 4,4'-bis(1,1-bis(3,5-dimethyl-1H-pyrrol-2-yl)ethyl)-1,1'-biphenyl, [H-BDPM-BPh] (), is synthesized via acid-catalyzed electrophilic aromatic substitution of 2,4-dimethylpyrrole with 4,4'-diacetylbiphenyl. Subsequent deprotonation of with -BuLi yields the corresponding Li-salt [Li-BDPM-BPh] (). Transmetalation involving and either CoCl or [Co(HMDS)] (HMDS = -N(Si(CH))) results in dinuclear Co(II) complexes.