Publications by authors named "K A Volodina"

Background: Contemporary research has shown that only a small proportion of high achieving young athletes continue to become successful senior athletes. However, there is a lack of empirical literature tracking the success of senior male and female athletes who were considered high achieving as a youth.

Hypothesis: Athletes of both sexes who are successful in youth categories (U18 and U20) are more likely to be successful senior athletes.

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Background: Overweight and obesity, low physical activity and lack of motivation to exercise are common among young adults. Thus, the objective of the study is to evaluate the efficiency of Nordic Walking for weight loss and improvement of functional and physiological state in young adults with overweight and obesity.

Methods: The study enrolled 77 students from Sechenov University with overweight and obesity aged from 17 to 23 years.

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Echocardiographic parameters were assessed in patients with non-ST segment elevation acute coronary syndrome, who underwent emergency percutaneous coronary intervention followed by various outpatient physical cardiac rehabilitation programs. The patients underwent physical rehabilitation for 3 months under conditions of diagnostic centre in the rehabilitation unit according to the standard program including in treadmill or bicycle exercise in the exercise therapy room or with Nordic walking in the main training block. After rehabilitation course, the left ventricular mass index significantly decreased and systolic volume and left ventricular ejection fraction significantly increased in both groups.

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Article Synopsis
  • Interaction between nanoparticles and biomolecules can lead to either compatible or harmful complexes, but the structural details of these interactions are not well understood.
  • This study investigates how a blood protein, bovine serum albumin, behaves when it is adsorbed onto silicon and germanium nanoparticles, especially when heated to 640 K.
  • The results show that the protein is more heat-resistant when attached to nanoparticles than in solution or solid, with germanium providing better heat resistance than silicon, which could promote safer use of these nanoparticles in biological applications.
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We present a high-yield method for the renaturation of negatively charged enzymes. The approach is based on the use of alumina nanoparticles, which after electrostatic interaction with denatured protein molecules, prevent their aggregation and make the process of refolding controllable. The method, demonstrated by the renaturation of several enzymes, is efficient, rapid, employs a minimal amount of reagents and even can be applied to renature mixture of the denatured enzymes.

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