Systematic Identification of circRNAs in Alzheimer's Disease.

Mammalian circRNAs are covalently closed circular RNAs often generated through backsplicing of precursor linear RNAs. Although their functions are largely unknown, they have been found to influence gene expression at different levels and in a wide range of biological processes. Here, we investigated if some circRNAs may be differentially abundant in Alzheimer's Disease (AD).

Influence of intragastric perfusion of aqueous spice extracts on acid secretion in anesthetized albino rats.

Background: The effect of spices on gastric acid secretion is variable. Their mechanism of action is also not well established.

Aim: To study the effect of spices on gastric acid secretion in anesthetized rats.

Effect of cadmium on the spermatogenesis of Rana hexadactyla Lesson.

A single subcutaneous injection of 0.5 mg cadmium chloride in Amphibian Ringer solution caused a significant decrease in secondary spermatogonial and primary spermatocytic stages in the semineferous tubules of frogs in 7 days. B3 cells of adenohypophysis and the activities of delta 5-3 beta-hydroxy steroid dehydrogenase and 17 beta-dehydrogenase in the Leydig cells were significantly increased in the same period.

The management of distal hypospadias with meatal-based, vascularized flaps.

In 63 children distal hypospadias was repaired using a meatal-based, vascularized flap. An acceptable glandular meatus was achieved in 62 children. Complications requiring further operation occurred in 5 children (8 per cent) and all were repaired successfully with only 1 other procedure.