Publications by authors named "K A Strauss"

Background: Advancements in cardiac catheterization have improved survival for pediatric congenital heart disease patients, but the associated ionizing radiation risks necessitate ethical consideration.

Methods: This study presents an empirical model, developed from 3131 unique pediatric procedures, to establish alert levels based on a patient's lateral thickness of the thorax for various procedural categories during diagnostic or interventional cardiac catheterization. The model uses linear regression of logarithmic reference air kinetic energy released per unit mass (KERMA) and air KERMA area product, also referred to as dose area product, to set alert levels at the top 95% and 99% of patient data.

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Steroid-refractory acute and chronic graft-versus-host disease (SR-a/cGvHD) represents a potential life-threatening complication following allogeneic stem-cell transplantation (allo-SCT). The JAK1/2-inhibitor ruxolitinib and the extracorporeal photopheresis (ECP) have been shown to significantly improve the overall response rate (ORR) in this setting. However, about 30-40 % of high-risk patients do not respond to monotherapy and/or experience side effects.

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Article Synopsis
  • * Results showed no deaths, significant discomfort, or severe device malfunctions post-MRI, with only two instances of minor atrial arrhythmia, both in patients with MR-conditional pacemakers.
  • * The findings support that MRI can be safely conducted in patients with CIEDs without adverse effects or changes in device performance, following proper protocols and monitoring.
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  • The study investigates the link between sports-related physical activity and heart issues in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC), noting that there's a lack of standard guidelines for assessing activity levels.
  • Researchers conducted a retrospective analysis of 124 ARVC patients, finding that higher levels of cumulative physical activity, particularly from sports, correlated with increased risks of heart failure and serious heart rhythm problems.
  • The results suggest that continuous tracking of physical activity can help identify risk levels for ARVC patients, highlighting that while sports activity is a significant factor, non-sports-related activities did not show a strong correlation with worsening heart conditions.
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Unlabelled: Alveolar bone supports and anchors teeth. The parathyroid hormone-related protein (PTHrP) pathway plays a key role in alveolar bone biology. Salt inducible kinases (SIKs) are important downstream regulators of PTH/PTHrP signaling in the appendicular skeleton where SIK inhibition increases bone formation and trabecular bone mass.

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