Publications by authors named "K A Skipper"

Background: Parents of children newly diagnosed with cancer require specialized education to provide care for their child at home, including the management of complex medication regimens.

Objective: To assess the complexity of home medication regimens in a cohort of newly diagnosed pediatric oncology patients.

Methods: We inventoried and categorized all discharge medications for each patient and used the Medication Regimen Complexity Index (MRCI) to quantify the complexity of the prescribed medication regimens.

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In cells, proteins rapidly self-assemble into sophisticated nanomachines. Bioinspired self-assembly approaches, such as DNA origami, have been used to achieve complex three-dimensional (3D) nanostructures and devices. However, current synthetic systems are limited by low yields in hierarchical assembly and challenges in rapid and efficient reconfiguration between diverse structures.

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Article Synopsis
  • The Children's Oncology Group (COG) Nursing Discipline aimed to gather information on how new diagnosis education is currently delivered across its member institutions, as practices were previously unknown.
  • A survey conducted from July to October 2023 received responses from 146 out of 227 COG institutions, revealing that while many rely on resources like the COG Family Handbook, less than half have a defined process for education.
  • The results indicate significant variability in practices, suggesting a need for more standardized approaches to improve new diagnosis education consistency across COG institutions.
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  • Colloids experience dipolar interactions when an external AC electric field is applied, leading to the formation of particle strings at high field strengths.
  • Researchers utilized the GMIN basin-hopping tool to analyze clusters of dipolar colloids with varying dipole strength and fixed orientation along the z axis, focusing on clusters containing 7 to 13 particles.
  • The study reveals that at moderate dipole strengths, distinct cluster shapes like polytetrahedral, octahedral, and spiral formations emerge, with advanced algorithms enabling the identification of these stable structures in bulk systems.
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Glioblastoma (GBM) is an aggressive brain tumor with a median survival of 15 months and has limited treatment options. Immunotherapy with checkpoint inhibitors has shown minimal efficacy in combating GBM, and large clinical trials have failed. New immunotherapy approaches and a deeper understanding of immune surveillance of GBM are needed to advance treatment options for this devastating disease.

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