Feedback from the 8th European Bioanalysis Forum Young Scientist Symposium.

After 2 years of COVID-19 restrictions, the 8th Young Scientist Symposium was organized again as a face-to-face meeting covering a broad array of scientific presentations. As in the previous editions, the meeting was organized by young scientists for young scientists under the umbrella of the European Bioanalysis Forum and in collaboration with academia. The traditional Science Café was again included as an interactive round table session.

The role of interleukin-6 trans-signalling on cardiovascular dysfunction in inflammatory arthritis.

Objectives: Cardiovascular (CV) mortality in RA patients is 50% higher than in the general population. There is increasing recognition that systemic inflammation is a major driver of this. IL-6 is implicated in cardiovascular disease (CVD) in the general population but its role in CVD in RA is undefined.

In Vivo Models for Inflammatory Arthritis.

In vivo mouse models of inflammatory arthritis are extensively used to investigate pathogenic mechanisms governing inflammation-driven joint damage. Two commonly utilized models include collagen-induced arthritis (CIA) and methylated bovine serum albumin (mBSA) antigen-induced arthritis (AIA). These offer unique advantages for modeling different aspects of human disease.

Alterations to adipose tissue morphology during inflammatory arthritis is indicative of vasculopathology in DBA/1 mice.

The physiologic function of adipose tissue is altered by the host's inflammatory response; the implications for maintaining human health and regulating inflammation-associated disease progression are ill defined. However, this cannot be investigated in humans, therefore the use of animal models is required. With the aim to determine morphological and molecular alterations to perivascular and organ-associated adipose tissues during inflammatory arthritis, collagen-induced arthritis (CIA) was established in male DBA/1 mice.

A comparison of two parasitoids (Hymenoptera: Encyrtidae) of the vine mealybug: rapid, non-discriminatory oviposition is favored when ants tend the host.

The encyrtid parasitoids Coccidoxenoides perminutus Girault and Anagyrus nr. sp. pseudococci (Girault) were compared in the laboratory as parasitoids of the mealybug Planococcus ficus (Signoret).