Publications by authors named "K A Shadrin"

Article Synopsis
  • Low-quality transplants affected by hypoxic injury can result in complications after surgery.
  • This research uses mathematical modeling to analyze how oxygen absorption through the liver impacts its metabolism when oxygen levels are low.
  • Findings indicate that lower oxygenation of the perfusion medium reduces oxygen uptake, requiring more energy for the liver's metabolism, while energy resources are optimally allocated among various metabolic processes.
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The study required o apply various modes of corresponding publications search through such international databases as RussiaScopus, Web of Science, Medline, The Cochrane Library, EMBASE, Global Health, CyberLeninka, RISC, eLIBRARY.RU. Actually, there are not less than one hundred definitions of constitution of individual.

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We studied the distribution of ferrihydrite nanoparticles isolated from bacteria Klebsiella oxytoca in the whole body in vivo and in a cultured isolated organ (liver). The possibility of controlling these nanoparticles in the body using a magnetic field was assessed. One hour after intravenous injection of ferrihydrite nanoparticles to mice, their accumulation was observed in the liver, lungs, and kidneys.

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It is shown that the transport of oxygen through the surface of the isolated perfused rat liver is an energy-dependent process that requires the energy of ATP hydrolysis.

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