Publications by authors named "K A Roecklein"
Chronotherapeutic interventions aimed at realigning the circadian system can improve depression. This systematic review evaluated the current evidence for circadian realignment as an antidepressant mechanism. A comprehensive search was conducted in studies that implemented a chronotherapeutic intervention in samples with depression and/or delayed sleep/circadian timing using PubMed, EMBASE, Cochrane Central Register of Controlled Trials (Wiley), Europe PMC, and PsycINFO.
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- * Participants kept a sleep diary, wore actigraphy devices, and provided urine samples to measure melatonin levels, with PIPR assessed after exposure to blue and red light.
- * Findings showed that lower PIPR responses were linked to reduced sleep quality and circadian rhythm function, suggesting age-related changes in light sensitivity may disrupt circadian regulation.
Background: Efforts to identify risk and resilience factors for anxiety severity and course during the COVID-19 pandemic have focused primarily on demographic rather than psychological variables. Intolerance of uncertainty (IU), a transdiagnostic risk factor for anxiety, may be a particularly relevant vulnerability factor.
Method: N = 641 adults with pre-pandemic anxiety data reported their anxiety, IU, and other pandemic and mental health-related variables at least once and up to four times during the COVID-19 pandemic, with assessments beginning in May 2020 through March 2021.
To isolate melanopsin contributions to retinal sensitivity measured by the post-illumination pupil response (PIPR), controlling for individual differences in non-melanopsin contributions including retinal irradiance is required. When methodologies to negate such differences present barriers, statistical controls have included age, baseline diameter, iris pigmentation, and circadian time of testing. Alternatively, the pupil light reflex (PLR) and calculations estimating retinal irradiance both reflect retinal irradiance, while the PLR also reflects downstream pathways.
View Article and Find Full Text PDFDo sleep and circadian characteristics predict alcohol use in adult drinkers?
Alcohol Clin Exp Res (Hoboken)
April 2024
Article Synopsis
- The study explored how baseline sleep and circadian rhythms relate to future alcohol use in healthy adults, focusing on individuals aged 21-42 years.
- Self-reported insomnia and longer sleep duration at baseline were significant predictors of increased alcohol consumption, including weekly drinks and binge episodes, over the following year.
- The findings indicate that insomnia symptoms may be a crucial target for interventions to reduce the risk of alcohol misuse, even more so than circadian factors.