Publications by authors named "K A ROSENKRANZ"
Background: Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment in major depressive disorder (MDD). However, intermittent theta-burst stimulation (iTBS) and rTMS protocols using 10 Hz stimulation frequency might differ in their effect on neuroplasticity and on clinical symptoms. This study compares the effect of iTBS and a novel 10 Hz-rTMS with shortened single session duration, on motor excitability and neuroplasticity and on clinical symptoms in MDD.
View Article and Find Full Text PDFLocoregional Management of Multiple Ipsilateral Breast Cancers: A Review.
Clin Breast Cancer
August 2024
The incidence of preoperatively diagnosed multiple ipsilateral breast cancer (MIBC) is increasing due to improved sensitivity of screening and preoperative staging modalities including digital breast tomosynthesis (3D breast mammography) and magnetic resonance imaging (MRI). The surgical management of MIBC remains controversial. Many surgeons continue to recommend mastectomy due to high local recurrence rates in patients with MIBC undergoing breast conservation therapy reported in historic, retrospective studies.
View Article and Find Full Text PDFArticle Synopsis
- Shared decision making (SDM) improves outcomes in breast cancer care, but it's not commonly used; a trial showed that conversation aids enhanced SDM and patient satisfaction when applied by trained surgeons.
- The SHared decision making Adoption Implementation Resource (SHAIR) Collaborative aims to integrate these conversation aids into standard preoperative care through an online learning platform that provides resources and support to clinical sites.
- The project will be conducted in two phases, starting with a pilot at five sites and expanding to 32 additional sites, using RE-AIM metrics to evaluate patient reach and collect data from various sources to assess the effectiveness of the implementation.
Significance Statement: We hypothesized that triple therapy with inhibitors of the renin-angiotensin system (RAS), sodium-glucose transporter (SGLT)-2, and the mineralocorticoid receptor (MR) would be superior to dual RAS/SGLT2 blockade in attenuating CKD progression in Col4a3 -deficient mice, a model of Alport syndrome. Late-onset ramipril monotherapy or dual ramipril/empagliflozin therapy attenuated CKD and prolonged overall survival by 2 weeks. Adding the nonsteroidal MR antagonist finerenone extended survival by 4 weeks.
View Article and Find Full Text PDFObjective: To develop the future of United States (US) surgical education leadership, surgical trainees and early career faculty who aspire to become program directors (PDs) must understand the potential career pathways and requisite skills and experience to become a general surgery residency PD. The objective of this study was to understand the demographics, career experiences, and professional satisfaction of US PDs in general surgery.
Design: An anonymous, cross-sectional survey utilizing a novel instrument.