Endoscopic light-guided choledochoduodenostomy in the treatment of the distal common bile duct obstruction.

Objective: Aim: Experimental justification for creation of bile offtake into the duodenum with minimally invasive methods in cases of obstruction of the distal part of common bile duct and failure of transpapillary interventions and studying the first results of such intervention application.

Patients And Methods: Materials and Methods: The anatomical relationships between the duodenum and the common bile duct in its distal parts starting from its retroduodenal part to the sphincter of Oddi were studied. The possibility of transillumination of the walls of the common bile duct and the duodenum by a light source introduced into the lumen of the common bile duct is determined.

Tailoring the pore structure of iron oxide core@stellate mesoporous silica shell nanocomposites: effects on MRI and magnetic hyperthermia properties and applicability to anti-cancer therapies.

Core-shell nanocomposites made of iron oxide core (IO NPs) coated with mesoporous silica (MS) shells are promising theranostic agents. While the core is being used as an efficient heating nanoagent under alternating magnetic field (AMF) and near infra-red (NIR) light and as a suitable contrast agent for magnetic resonance imaging (MRI), the MS shell is particularly relevant to ensure colloidal stability in a biological buffer and to transport a variety of therapeutics. However, a major challenge with such inorganic nanostructures is the design of adjustable silica structures, especially with tunable large pores which would be useful, for instance, for the delivery of large therapeutic biomolecule loading and further sustained release.

Surgical treatment results in patients with defects of the integumentary tissues of the trunk and limbs of mechanical origin.

This study aimed to develop and implement a universal method for the quantitative assessment of treatment effectiveness in patients with skin and underlying soft tissue defects of the trunk and extremities. The study involved 242 patients, including 46 patients with upper extremity injuries, 179 with lesions of lower extremity tissues, and 17 patients with defects of the integumentary tissues of the trunk. The greatest treatment effectiveness was observed in patients with upper limb injury: excellent result - 60.

AFFECTIVE-COGNITIVE INDICATOR OF EMOTIONAL INTELLIGENCE FORMEDNESS IN HIGH SCHOOLERS WITH INTELLECTUAL DISABILITIES.

Objective: The aim is to determine the peculiarities of the affective-cognitive indicator of emotional intelligence in high schoolers with intellectual disabilities.

Patients And Methods: Materials and methods: The study, which was conducted during 2019-2020, involved 76 high schoolers in the age of 14-17 who studied in the 7-9th grades in Kyiv schools (Ukraine) (45 high schoolers with intellectual disabilities and 31 high schoolers with normative development). The diagnosis of the high schoolers' ability to perceive, understand and identify emotions; to assimilate emotions in thoughts, to stimulate thought processes with the help of emotions was carried out.

SEBORRHEIC KERATOSIS: CURRENT STATE OF THE PROBLEM.

Objective: The aim is to identify age, gender, clinical and morphological features of seborrheic keratosis.

Patients And Methods: Material and methods: The study used biopsy material from 196 patients with a clinical diagnosis of "Seborrheic keratosis". In all cases, when studying directions for pathohistological examination, the authors analyzed gender and age characteristics, as well as localization of seborrheic keratosis.