Publications by authors named "K A Pacheco"

Background: Despite the utility of the beryllium lymphocyte proliferation test (BeLPT), distinguishing sarcoidosis, a disease of unknown etiology, from chronic beryllium disease (CBD), has long posed a diagnostic challenge. It is unclear if beryllium-exposed sarcoidosis cases (Be-exp-Sarc) are clinically distinct from CBD, or are misdiagnosed cases of CBD.

Methods: We performed a case-case study of 40 beryllium-exposed individuals diagnosed with Be-exp-Sarc compared to 40 frequency-matched CBD cases.

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Background: With the rapid evolution of artificial intelligence (AI), particularly large language models (LLMs) such as ChatGPT-4 (OpenAI), there is an increasing interest in their potential to assist in scholarly tasks, including conducting literature reviews. However, the efficacy of AI-generated reviews compared with traditional human-led approaches remains underexplored.

Objective: This study aims to compare the quality of literature reviews conducted by the ChatGPT-4 model with those conducted by human researchers, focusing on the relational dynamics between physicians and patients.

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Purpose: Adolescent and young adult patients occupy a clinically transitional space between pediatric and adult care. Youth with chronic conditions and special healthcare needs may have trouble accessing and receiving appropriate care in this transition, which may lead to patient safety issues and medicolegal risks for physicians. The objectives of this article were to explore patient safety issues and identify medicolegal risks for physicians.

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Article Synopsis
  • - Allergic contact dermatitis is a skin condition marked by red, swollen, and scaly areas, often caused by specific immune responses to low-molecular-weight allergens like metals and preservatives.
  • - Biomedical devices containing these allergens can trigger sensitization and inflammatory responses, leading to internal symptoms such as swelling and pain, which may extend to localized or systemic dermatitis.
  • - This review focuses on reactions to orthopedic implants, the most common type of internal metal devices, and discusses diagnostic methods, interpretations, and treatment strategies for related immune reactions in various medical appliances.
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