The disruption of Cu homeostasis is associated with the pathogenesis of many diseases and can result in alterations in Cu isotope fractionation. Changes in the Cu isotope ratio (Cu/Cu) of body fluids and tissues have been observed in liver disorders, cancers, and other diseases, displaying diagnostic/prognostic potential. However, it is not entirely clear whether certain physiological or lifestyle factors may also influence the bodily Cu isotopic composition, potentially obfuscating the signature of the pathology.
View Article and Find Full Text PDFObjective: This study aimed to investigate two key aspects of scalp high-frequency oscillations (HFOs) in pediatric focal lesional epilepsy: (1) the stability of scalp HFO spatial distribution across consecutive nights, and (2) the variation in scalp HFO rates in response to changes in antiseizure medication (ASM).
Methods: We analyzed 81 whole-night scalp electroencephalography (EEG) recordings from 20 children with focal lesional epilepsy. We used a previously validated automated HFO detector to assess scalp HFO rates (80-250 Hz) during non-rapid eye movement (NREM) sleep.
MicroPubl Biol
December 2024
The evolution of developmental rates may drive morphological change. develops nearly twice as slowly as . encodes a hydroxylase required for synthesizing ubiquinone, and mutant slow growth phenotypes can be rescued by supplying animals with a ubiquinone precursor analogue, 2,4-dihydroxybenzoate.
View Article and Find Full Text PDFThe third-person effect describes a tendency to estimate the influence of mass communication on others ("third persons") as being stronger than on oneself and this has been well documented in previous research. Though a first-person effect has also been postulated for desirable mass communication messages (for ex. non-profit advertisements or public service announcements (PSAs)), for which reporting more influenceability of the self as compared to others should be a means to self-enhance, it has not been found in the two named meta-analyses.
View Article and Find Full Text PDFUnlabelled: Understanding the biotic drivers of diversity is a major goal of microbial ecology. One approach towards tackling this issue is to interrogate relatively simple communities that are easy to observe and perturb. Figs (syconia) of the genus represent such a system.
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