Publications by authors named "K A Massey"
Article Synopsis
- Obesity is linked to a rise in autoimmune diseases, especially in women.
- In female mice that became overweight, researchers found more signs of inflammation in the brain that could lead to multiple sclerosis (MS).
- The study revealed that being overweight causes changes in certain immune cells, and these changes were influenced by hormones and fat in the body.
Article Synopsis
- Riboflavin transporter deficiency type 2 (RTD2) is a rare genetic disorder caused by mutations in the SLC52A2 gene, affecting riboflavin transporters and leading to neurodegeneration, particularly in motoneurons.
- Previous research on RTD2 using human induced pluripotent stem cells (iPSCs) revealed issues with energy metabolism and cytoskeletal structure in affected motoneurons.
- New findings show that astrocytes derived from RTD2 iPSCs maintain normal morphology and survival rates, suggesting that RTD2 does not impair astrocyte function like it does in motoneurons.
Firefighters wear personal protective equipment to protect them from the thermal and chemical environment in which they operate. The self-contained breathing apparatus (SCBA) provides isolation of the airway from the hazardous fireground. National standards limit SCBA weight, however, integration of additional features could result in an SCBA exceeding the current limit.
View Article and Find Full Text PDFBackground And Objectives: AQP4 antibody-positive NMOSD (AQP4-NMOSD), MOG antibody-associated disease (MOGAD), and seronegative NMOSD (SN-NMOSD) are neuroautoimmune conditions that have overlapping clinical manifestations. Yet, important differences exist in these diseases, particularly in B-cell depletion (BCD) efficacy. Yet, the biology driving these differences remains unclear.
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