Publications by authors named "K A Lo"
Introduction: TWe investigated impacts of particulate matter with an aerodynamic diameter of less than 2.5 μm (PM), relative humidity (RH), and temperature on sleep stages and arousal.
Materials And Methods: A cross-sectional analysis involving 8,611 participants was conducted at a sleep center in Taipei.
Article Synopsis
- SGLT2 inhibitors have been linked to reduced incidences of heart failure (HF) and related hospitalizations, but the exact mechanisms behind these benefits in invasive heart measurements are not well understood.
- A systematic review of randomized trials using PRISMA guidelines examined the impact of SGLT2i on heart function, measuring hemodynamics before and after treatment through right heart catheterization.
- The analysis of 3 studies involving 145 patients showed that SGLT2i significantly lowered pulmonary capillary wedge pressure at rest and during exercise, indicating potential improvements in heart function, although the effect on mean pulmonary artery pressure was not statistically significant.
Autosomal Dominant Polycystic Kidney Disease (ADPKD) results in progressive cysts that lead to kidney failure, and is caused by heterozygous germline variants in PKD1 or PKD2. Cyst pathogenesis is not definitively understood. Somatic second-hit mutations have been implicated in cyst pathogenesis, though technical sequencing challenges have limited investigation.
View Article and Find Full Text PDFHerpes simplex virus type 1 (HSV-1) is the leading pathogen in the maxillo-facial region, affecting millions of individuals worldwide. Its periodic reactivation aligns with the most common course pattern of periodontal disease. The present study used RNA sequencing to investigate the transcriptomes of human gingival fibroblasts (HGFs) following HSV-1 infection from the early to late stages (12-72 h).
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