Contact Lens Solutions and Contact Lens Discomfort: Examining the Correlations Between Solution Components, Keratitis, and Contact Lens Discomfort.

Objectives: This article will examine the current literature, as it relates to contact lens discomfort (CLD) secondary to contact lens solutions. The reader will better understand the characteristics of contact lenses, as they uniquely interact with each type of contact lens solution and also gain a better comprehension of the components of contact lens solution such as preservatives, surfactants, and chelating agents, which may contribute to discomfort. By investigating corneal staining theory and the mechanisms that contribute to its presence, the reader will gain insight into this clinical finding, which relates to selection of contact lens solutions.

A comparison of a traditional and wavefront autorefraction.

Purpose: To evaluate the agreement between the autorefraction function of the Canon RK-F2, an autorefractor/keratometer based on the ray deflection principle, and the Carl Zeiss Vision i.Profiler(Plus), an wavefront aberrometer, compared with each other and with a noncycloplegic subjective refraction.

Methods: Objective refraction results obtained using both instruments were compared with noncycloplegic subjective refractions for 174 eyes of 100 participants.

Detection of macular function changes in early (AREDS 2) and intermediate (AREDS 3) age-related macular degeneration.

Background/aim: To evaluate if retinal sensitivity values obtained with a dedicated (screening) device can be used to functionally identify early and intermediate age-related macular degeneration (ARMD).

Methods: A fully automatic fundus perimeter combined with an image-stabilized scanning laser ophthalmoscope was used in 200 ARMD patients (319 eyes) in 5 study sites. The age-matched control group consisted of 200 normals.

Evaluation of corneal staining and patient preference with use of three multi-purpose solutions and two brands of soft contact lenses.

Purpose: Clinical signs and symptoms vary depending on contact lens brand, lens care products, or a combination of the two. Studies evaluated corneal staining and subject preference associated with three multipurpose solutions (MPS) and two soft contact lens brands.

Methods: Two sites conducted the randomized, investigator-masked, 2-month crossover studies.

Differentiating contact lens induced warpage from true keratoconus using corneal topography.

Purpose: Superior corneal flattening associated with inferior corneal steepening is a videokeratoscopic topography pattern that usually describes both keratoconus and contact lens induced warpage. To differentiate these two conditions topographically, we analyzed ten different corneal topographic shape variables and found that two distinct conditions were described. Three unique measurements of corneal geometry: shape factor (SF), irregularity (CIM), and apical toricity (TKM) were analyzed and evaluated as an additional method for differentiating these two conditions.