Publications by authors named "K A LEMON"

Strains of two novel species were cultured from samples of human nostrils and skin collected in the United States and Botswana. These strains demonstrated growth on Columbia Colistin-Nalidixic Acid agar with 5% sheep blood and in liquid media (brain heart infusion and tryptic soy broth) supplemented with Tween 80, a source of the fatty acid oleic acid. Cells were Gram-positive, non-spore-forming, non-motile bacilli that showed catalase but not oxidase activity.

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Unlabelled: e species are globally ubiquitous in human nasal microbiota across the lifespan. Moreover, nasal microbiota profiles typified by higher relative abundances of are often positively associated with health. Among the most common human nasal species are , , and .

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Article Synopsis
  • - The study investigates the feasibility of using wastewater-based epidemiology (WBE) and whole-genome sequencing (WGS) to detect and differentiate between human and avian strains of Influenza A viruses (IAVs) across Northern Ireland.
  • - Between August and December 2022, wastewater samples from six treatment facilities revealed a constant presence of IAVs, with varied proportions of human and avian strains, though no strong correlation was found with clinical IAV data from the region.
  • - The findings suggest that WBE can effectively monitor circulating IAV strains, offering a valuable approach for ongoing surveillance and potential prevention of influenza outbreaks through genetic analysis.
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  • Nasal colonization by certain bacteria increases infection risk, while others are linked to health; this study used human nasal epithelial organoids (HNOs) to explore these dynamics.
  • HNOs were successfully colonized with three bacterial species for up to 48 hours, showing minimal harm and allowing for the bacteria to localize in the mucus.
  • The research identified specific immune responses to the bacterial species, indicating that some bacteria trigger inflammation while others modulate immune signaling without causing infection.
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  • * Laboratory tests confirmed the presence of a low-pathogenicity avian influenza virus (LPAIV) subtype H6N1, affecting 15 premises in Northern Ireland and spreading to 13 in the Republic of Ireland and six in Great Britain.
  • * The outbreak resulted in the culling of over 2 million birds to control the spread, highlighting the significant economic consequences and the need for swift action during LPAIV outbreaks.
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