The feature with Gene ID 108083276 was determined to be an ortholog of absent, small, or homeotic discs 1 ( ). Two isoforms, ash1-PB and ash1-PC, were constructed on the Muller D element using the GEP annotation protocol. The second coding exon of includes an insertion translated into 18 additional amino acids compared to the protein and is supported by RNA-Seq coverage, the lack of splice junction predictions, and multiple gene predictors.
View Article and Find Full Text PDFBackground: Adults who maintain ideal cardiovascular health (CVH) profiles up to midlife have lower risk of several chronic diseases and better quality of life. Some evidence suggests that individual-level exposures earlier in life shape midlife CVH, but the impact of neighborhood-level exposures over the life course remains understudied.
Methods And Results: Participants were 3017 Black and White men and women aged 18 to 30 years at baseline (1985-1986), recruited from Birmingham, Alabama; Minneapolis, Minnesota; Chicago, Illinois; and Oakland, California, as part of the CARDIA (Coronary Artery Risk Development in Young Adults) study.
Background: Implications of lifelong, perceived discrimination on nutrient intake during the preconception period are unclear.
Objective: The objective was to identify associations between perceived discrimination and consumption of specific nutrients associated with risk of adverse pregnancy outcomes.
Design: This is a secondary data analysis of the prospective Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be cohort.
J Adolesc Health
November 2024
Purpose: Persistent self-control in the context of upward mobility in low-income adolescents, especially those of color, may have physiological costs, such as greater risks of developing cardiometabolic diseases in young adulthood. One potential mechanism linking self-control to cardiometabolic health is epigenetic age acceleration (EAA). However, little is known regarding the association between high self-control and EAA, as well as what factors may play protective roles.
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