Publications by authors named "K A Kershaw"

The feature with Gene ID 108083276 was determined to be an ortholog of absent, small, or homeotic discs 1 ( ). Two isoforms, ash1-PB and ash1-PC, were constructed on the Muller D element using the GEP annotation protocol. The second coding exon of includes an insertion translated into 18 additional amino acids compared to the protein and is supported by RNA-Seq coverage, the lack of splice junction predictions, and multiple gene predictors.

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Background: Adults who maintain ideal cardiovascular health (CVH) profiles up to midlife have lower risk of several chronic diseases and better quality of life. Some evidence suggests that individual-level exposures earlier in life shape midlife CVH, but the impact of neighborhood-level exposures over the life course remains understudied.

Methods And Results: Participants were 3017 Black and White men and women aged 18 to 30 years at baseline (1985-1986), recruited from Birmingham, Alabama; Minneapolis, Minnesota; Chicago, Illinois; and Oakland, California, as part of the CARDIA (Coronary Artery Risk Development in Young Adults) study.

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Background: Implications of lifelong, perceived discrimination on nutrient intake during the preconception period are unclear.

Objective: The objective was to identify associations between perceived discrimination and consumption of specific nutrients associated with risk of adverse pregnancy outcomes.

Design: This is a secondary data analysis of the prospective Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be cohort.

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Article Synopsis
  • The study analyzed how different levels of psychosocial stress impact the risk of cardiovascular disease (CVD) over time, using data from the Multi-Ethnic Study of Atherosclerosis (MESA) involving over 6,300 adults.
  • Researchers found five distinct subgroups of psychosocial stress based on self-reported data, with 'high discrimination' being linked to a significantly increased risk of CVD events, even after adjusting for other health factors.
  • Social support, neighborhood cohesion, and physical activity did not significantly alter the relationship between psychosocial stress and CVD risk, indicating that high levels of discrimination and chronic stress are critical factors for cardiovascular health outcomes.
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Purpose: Persistent self-control in the context of upward mobility in low-income adolescents, especially those of color, may have physiological costs, such as greater risks of developing cardiometabolic diseases in young adulthood. One potential mechanism linking self-control to cardiometabolic health is epigenetic age acceleration (EAA). However, little is known regarding the association between high self-control and EAA, as well as what factors may play protective roles.

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