Publications by authors named "K A Halmi"

Article Synopsis
  • - This study is the first large-scale examination of rare copy number variants (CNVs) in anorexia nervosa (AN), involving data from 7,414 AN cases and 5,044 controls to explore their potential genetic links to the disorder.
  • - The researchers investigated both well-known syndromic CNVs and those associated with other diseases but found no significant links between these variants and AN; however, they identified 21 potential CNV regions that may play a role in AN risk, particularly in areas related to metabolic and neurodevelopmental factors.
  • - Ultimately, the findings suggest that rare CNVs have a limited impact on the development of AN, aligning it with other psychiatric disorders like bipolar disorder, and indicate that
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Objective: Individuals with anorexia nervosa (AN), restricting type demonstrate unique emotional responses to hedonically positive stimuli beyond eating disorder (ED)-related stimuli. The goal of this study was to evaluate differences in responses to five types of emotionally positive stimuli among acutely ill anorexia nervosa (IAN), restricting type patients, weight-recovered anorexia patients (WRAN), and healthy controls (HCs) using affect modulated startle response (AMSR) as an objective measure.

Method: A total of 28 participants were recruited (n=28).

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Article Synopsis
  • This study explores the role of genetics in the age of onset of anorexia nervosa (AN) by analyzing data from a large genome-wide association study involving 9,335 cases and 31,981 control participants.
  • Researchers found significant genetic variations linked to typical-onset AN and identified different genetic correlations for early-onset (before age 13) and typical-onset AN, indicating distinct biological influences.
  • Results suggest a genetic relationship between the age at menarche and early-onset AN, implying that earlier menarche may increase the risk of developing AN at a younger age.
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