Objective: Traumatic hemorrhagic cerebral contusions are a well-established cause of morbidity and mortality in neurosurgery. This study aimed to determine prognostic factors for long-term functional outcomes and longitudinal contusion volume changes in traumatic brain injury (TBI) patients.
Methods: Data from 285 patients with traumatic cerebral contusions were retrospectively reviewed to identify variables predictive of initial contusion volume, contusion expansion on short-term follow-up imaging, and functional outcomes according to the modified Rankin Scale (mRS).
Background: Similar neuroimaging abnormalities are reported in post-COVID patients and patients with AD. Moreover, COVID-19 and Alzheimer's Disease (AD) share genetic vulnerabilities and have similar cognitive symptoms of COVID (e.g.
View Article and Find Full Text PDFBackground: Semantic memory assessments are sensitive indicators of cognitive decline in pre-clinical Alzheimer's Disease (AD), with slowed reaction time and diminished accuracy serving as markers for amyloid accumulation. We introduce the Semantic Stroop Test-a brief (4.3 minute), automated semantic retrieval and executive function task included in the California Cognitive Assessment Battery (CCAB).
View Article and Find Full Text PDFBackground: Cognitive-test scores in the bottom 7% of a normative distribution (z-score < -1.50) are an essential component of the diagnosis of Mild Cognitive Impairment (MCI). However, different patients show MCI-compatible performance when evaluated using scoring models that account for the influences of different demographic variables (e.
View Article and Find Full Text PDFBackground: The administration of cognitive tests in patients' homes facilitates access by underserved communities and increases testing capacity and efficiency. However, the validity of at-home computerized cognitive tests is often questioned because of limitations in examiner monitoring, distractions, environmental noise, and potential cheating. Here, we compare performance of the computerized and proctored California Cognitive Assessment Battery (CCAB) when administered at-home or in the laboratory using otherwise identical procedures.
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