Publications by authors named "K A Groesch"
Mapping of the Deep Epigastric Vessels Stratified by Body Mass Index (BMI).
J Minim Invasive Gynecol
December 2024
Objective: To investigate the positioning of deep epigastric vessels in obese patients to determine the need to redefine laparoscopic port placement 'safe zones' based on body habitus.
Design: Retrospective case series.
Setting: University-affiliated 500-bed hospital.
Objective: To compare in-hospital and neurodevelopmental (ND) outcomes between very preterm infants conceived spontaneously and those conceived utilizing in vitro fertilization (IVF).
Study Design: A 10-year retrospective study of a large regional, mixed urban and rural population was conducted. IVF conceived infants born <32 0/7 weeks gestational age (GA) were matched 1:2 to control patients who did not undergo any documented assisted reproductive technology (ART) based on GA, birth weight and gender.
Article Synopsis
- Endometriosis is linked to changes in gut and urinary microbiomes, which can be influenced by the number of sexual partners and the type of treatments patients receive.
- Researchers collected and analyzed samples from patients with endometriosis and control individuals to understand the effects of hormonal therapy and surgical interventions on microbial profiles.
- Results showed that higher sexual partner exposure can worsen microbial imbalances in endometriosis patients, potentially reducing the effectiveness of treatments like hormone therapy and surgery.*
Article Synopsis
- Epithelial ovarian cancer (OC) is a highly lethal cancer affecting women, with significant mortality rates and challenges in treatment due to resistance to platinum-based chemotherapy.
- The study explored the relationship between peripheral immune profiles, peritoneal microbial features, and the chemotherapy response in patients with OC, finding that inflammation levels at surgery were linked to longer disease-free intervals.
- Results indicated that unique microbial features in the peritoneal fluid could help in predicting responses to chemotherapy, though self-rated health scores did not prove to be reliable indicators of immune status in these participants.
Endometrial cancer (EC) is the most prevalent gynecological malignancy. Abnormal accumulation of sterol-O-acyl transferase 1 (SOAT1) and SOAT1-mediated cholesterol ester (CE) contributes to cancer progression in various malignancies, including ovarian cancer. Therefore, it was hypothesized that similar molecular changes may occur in EC.
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