Upgrading the front end of the petawatt-class PEARL laser facility.

A new front-end laser system with optical synchronization of chirped femtosecond and pump pulses for the petawatt laser complex PEtawatt pARametric Laser (PEARL) has been developed. The new front-end system provides a broader femtosecond pulse spectrum, temporal shaping of the pump pulse, and a significant increase in the stability of the parametric amplification stages of the PEARL.

Efficacy and Safety of Divaza for the Correction of Oxidative Disturbances in Patients with Cerebral Atherosclerosis: A Randomized Controlled Trial.

Objective: The objective of this study was to determine if Divaza, a drug with nootropic and antioxidant effects, was safe and effective for the correction of oxidative disturbances and to stabilize cognitive impairment in patients with cerebral atherosclerosis.

Study Design: The study design consisted of a 12-week multicenter, randomized, double-blind, placebo-controlled, prospective trial in parallel groups.

Setting: The setting in which the study was conducted comprised 10 clinical centers across the Russian Federation.

[Possibilities and perspectives of berlition usage in the treatment of alcohol polyneuropathy].

A comparison study of efficacy and tolerability of the drug berlition 300 oral and berliton 300 U and vitamin B1 has been conducted in 56 patients with alcohol polyneuropathy (15 female, 41 male, mean age 42.6 years). The key mechanisms of berlition action are increasing of endoneural blood flow, strengthening of antioxidant system functioning and reduction of "oxidative stress" intensity; improvement of glucose consumption and restoring of nerve energetic balance as well as intensification of nerve growth factor releasing and nerve growth acceleration after its experiment cutting or squeezing.