Publications by authors named "K A Dukes"

Introduction: Hospitalizations present an opportunity to initiate naltrexone for patients with alcohol use disorder (AUD). Understanding factors associated with post-hospitalization adherence could inform practice.

Methods: This study is a secondary analysis of a clinical trial in which patients with AUD were randomized to oral (PO) versus long-acting injectable (LAI) naltrexone at hospital discharge.

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  • - The study examines antibiotic overuse in walk-in clinics, focusing on the effectiveness of a specific metric that tracks antibiotic prescribing for respiratory tract diagnoses (RTDs) while excluding complicating factors.
  • - Data from 331,496 clinic visits between 2018-2022 revealed that 36.5% met RTD criteria, with 36.7% of those receiving antibiotics; factors like patient age and comorbidities influenced prescribing rates.
  • - Provider interviews indicated that the RTD metric is acceptable for assessing antibiotic prescribing practices, suggesting it has validity, but further research is needed to evaluate its effectiveness as a feedback tool.
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  • - The study examines the value and potential harms of ordering preoperative urine cultures, particularly in non-urological surgeries, by interviewing a diverse group of medical professionals at Veterans Affairs hospitals.
  • - Key findings show that surgeons are anxious about missing signs of infection and perceive risks associated with not conducting urine cultures, which complicates the potential for changing these practices.
  • - Suggestions for improving acceptance of de-implementing urine cultures include leadership support and engagement from peers to counteract concerns about perceived risks.
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Importance: Survival for out-of-hospital cardiac arrest (OHCA) varies widely across emergency medical service (EMS) agencies in the US. However, little is known about which EMS practices are associated with higher agency-level survival.

Objective: To identify resuscitation practices associated with favorable neurological survival for OHCA at EMS agencies.

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Background: A substantial proportion of patients undergoing hemodialysis carry in their noses, and carriers are at increased risk of bloodstream infections. Our pragmatic clinical trial implemented nasal povidone-iodine (PVI) decolonization for the prevention of bloodstream infections in the novel setting of hemodialysis units.

Objective: We aimed to identify pragmatic strategies for implementing PVI decolonization among patients in outpatient hemodialysis units.

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