Metabolically active and polyploid renal tissues rely on graded cytoprotection to drive developmental and homeostatic stress resilience.

Body tissues are frequently exposed to stress, from toxic byproducts generated during cellular metabolism through to infection or wounding. Although it is well-established that tissues respond to exogenous injury by rapidly upregulating cytoprotective machinery, how energetically demanding tissues - vulnerable to persistent endogenous insult - withstand stress is poorly understood. Here, we show that the cytoprotective factors Nrf2 and Gadd45 act within a specific renal cell subtype, the energetically and biosynthetically active 'principal' cells, to drive stress resilience during Drosophila renal development and homeostasis.

Survey of 1977 crop year preharvest corn for vomitoxin.

Fifty-two preharvest corn samples were collected in mid-October 1977 from 26 farms in a four-county area of northwest Ohio. Vomitoxin ranging from 0.5 to 10 microgram/g was found in 24 of the samples.

Evaluation of Sclerotinia sclerotiorum as a potential mycotoxin producer on soybeans.

Solvent extracts of Sclerotinia sclerotiorum sclerotia were nontoxic to mice and chicken embryos; psoralens were not detected. Solvent extracts of soybeans inoculated with 10 strains of S. sclerotiorum were toxic on injection but nontoxic on per os administration to mice.