Publications by authors named "K A Bogaert"
Background: A subset of developmental disorders (DD) is characterized by disease-specific genome-wide methylation changes. These episignatures inform on the underlying pathogenic mechanisms and can be used to assess the pathogenicity of genomic variants as well as confirm clinical diagnoses. Currently, the detection of these episignature requires the use of indirect methylation profiling methodologies.
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- Brown seaweeds are vital to coastal ecosystems, but they are threatened by climate change, prompting a detailed genetic study.
- The research traced the evolutionary history of brown algae, highlighting significant gene families and metabolic pathways related to their adaptation and functional diversity.
- Findings also indicated that the integration of large viral genomes has played a crucial role in shaping the genetics and traits of brown algal species over time.
Objective: Rising maternal morbidity and mortality in the United States is a complex problem and is often tied to the postpartum period. Postpartum visits are poorly attended leading to gaps in contraception, mental health care, and care for chronic conditions. mHealth, health care supported by mobile technologies, has been shown to improve antenatal care adherence.
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- The transition to complex multicellularity in eukaryotes is a significant evolutionary development, with brown algae being a less understood example.
- Recent advancements in genetic and genomic technologies have facilitated in-depth studies of brown algae development, shedding light on important topics like pattern formation and sexual differentiation.
- The Review also addresses unanswered questions regarding key regulators, cell type definitions, and developmental plasticity, suggesting that brown algae could become important model organisms in studying multicellular evolution and body plan diversity.