Publications by authors named "K A Baines"

Simultaneous observations of and in Jupiter's northern infrared aurora were conducted on 02 June 2017 using Keck-NIRSPEC to produce polar projection maps of radiance, rotational temperature, column density, and radiance. The temperature variations within the auroral region are K, generally consistent with previous studies, albeit with some structural differences. Known auroral heating sources including particle precipitation, Joule heating, and ion drag have been examined by studying the correlations between each derived quantity, yet no single dominant mechanism can be identified as the main driver for the energetics in Jupiter's northern auroral region.

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  • A study in Ecuador examined the effects of PFASs and pesticides on lung function in 381 adolescents, measuring their exposure to specific substances and assessing lung health over six years.
  • Individual substances like PFOA, glyphosate, and ethylene thiourea showed slight associations with lung function improvements, but most other exposures did not have significant effects.
  • Overall, the results suggest no strong evidence linking PFASs and pesticides with lung function changes in this population, especially after adjusting for various factors like household income and tobacco exposure.
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Mothers with asthma or atopy have a higher likelihood of having autistic children, with maternal immune activation in pregnancy implicated as a mechanism. This study aimed to determine, in a prospective cohort of mothers with asthma and their infants, whether inflammatory gene expression in pregnancy is associated with likelihood of future autism. Mothers with asthma were recruited to the Breathing for Life Trial.

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Antibody-drug conjugates have transformed treatment for urothelial cancer (UC). Enfortumab vedotin is the new standard of care in the first-line setting for advanced UC. A personalised approach targeting HER2 in UC is currently being explored.

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  • Bronchiectasis is a chronic lung disease affecting many, especially Indigenous populations in wealthy countries, and currently has no approved treatments.
  • A randomized controlled trial (RCT) aims to test the mucoactive agent erdosteine over 12 months to see if it reduces acute respiratory exacerbations in children and adults aged 2-49 with bronchiectasis.
  • The study will also evaluate the impact of erdosteine on quality of life, exacerbation duration, hospitalizations, lung function, and its overall cost-effectiveness.
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