The hepatic blood flow and monooxygenase system activity were studied in 68 ischemic [correction of coronary] heart disease patients aged 37-68 [correction of 40-80] years who had functional class III-IV effort angina and 12 healthy volunteers matched by age. An analysis of the finding indicated that in patients with angina pectoris, the hepatic blood flow index decreased, the pharmacokinetic parameters of antipyrin impaired, the degree of these impairments depended on the severity of the clinical course of angina pectoris.
View Article and Find Full Text PDFThe authors describe a new method of X-ray endovascular destruction of the adrenal in patients with arterial hypertension and hyperaldosteronism. Destruction of the adrenal is accomplished by acute occlusion of its venous channel by introduction of a 3% thrombovar solution through a catheter installed in the central vein of the suprarenal gland. This method was applied in 22 patients with arterial hypertension; essential hypertension with secondary hyperaldosteronism was found in 18 of them, renoparenchymatous hypertension in 2, aldosteroma of the left adrenal in one, and Itsenko-Cushing's disease in one patient.
View Article and Find Full Text PDFThe authors performed a comprehensive study of the recovery processes in the myocardium after occlusion of the coronary artery in 126 white rats under the effect of a long-term treatment with propranolol (0.5 mg/kg). The drug reduced the size of necrosis by 2.
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