[A case of ischemic stroke in a patient with probable CADASIL].

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy CADASIL) is a rare inherited disorder in which thickening of the walls of small and medium-sized blood vessels blocks blood flow to the brain. Diagnosis of CADASIL is based on clinical presentation, neuroimaging findings, and genetic predisposition. This disease is uncommon in children; typically, symptoms manifest in individuals between the ages of 20 and 40, though some may exhibit symptoms later in life.

[Structural and functional features of the main arteries of the brain and tumor necrosis factor-alpha in people with chronic non-infectious diseases].

Objective: To investigate the structural and functional characteristics of the carotid and vertebral arteries and their relationship with tumor necrosis factor-alpha (TNF-α) levels in patients with chronic non-infectious diseases (CNIDs), considering sex differences.

Unlabelled: Material and Methods. A retrospective analysis of clinical and laboratory data of 760 patients with chronic non-communicable diseases (average age 52.

[Prevalence, age and gender features of chronic kidney disease in patients with diabetes mellitus].

Aim: To study the prevalence, age and gender characteristics of chronic kidney disease (CKD) in patients with diabetes mellitus (DM).

Materials And Methods: In a case-control study, clinical and laboratory data were analyzed in 683 patients with DM (4.6% of patients with type 1 DM and 95.

[New data on the pathophysiology of ischemic stroke: epigenetic mechanisms in focus].

Epigenetics is a branch of molecular biology that studies modifications able to change gene expression without changing the DNA sequence. Epigenetic modulations include DNA methylation, histone modifications, and noncoding RNAs. These heritable and modifiable gene changes can be caused by lifestyle and dietary factors.

[Urolithiasis in HIV-positive patients: prevalence and risk factors].

Today, the total number of people living with the human immunodeficiency virus (HIV) is 43.8 million. From the moment of infection to the terminal stage of the disease, the risk of stone formation progressively increases.