Publications by authors named "Jyotsna Kawadkar"
Cellulosic nanomaterials have significantly promoted the development of sensing devices, drug delivery, and bioreactor processes. Their synthetic flexibility makes them a prominent choice for immobilizing biomolecules or cells. In this work, we developed a practical and user-friendly approach to accessing cellulose nanoparticles (CNPs).
View Article and Find Full Text PDFThe maintenance of machinery requires its operational understanding and a toolbox for repair. The methods for the precision engineering of native proteins meet a similar requirement in biosystems. Its success hinges on the principles regulating chemical reactions with a protein.
View Article and Find Full Text PDFArticle Synopsis
- Post-translational modifications (PTMs) like SUMOylation play a key role in regulating protein functions and are essential for various cellular processes, including signal transduction and stress responses.
- Unlike ubiquitination, SUMOylation can significantly alter a protein's structure, stability, and interactions, highlighting its importance in cellular regulation, and its deregulation is linked to diseases.
- Despite the challenges in detecting SUMOylation due to its low occurrence, bioinformatics and mass spectrometry techniques have been developed to identify and validate SUMO modifications, aiding in the understanding of their biological functions.