Publications by authors named "Jyoti Kadian"
Efficacy and Safety of Novel Thiazolidinedione Rivoglitazone in Type-2 Diabetes a Meta-Analysis.
Indian J Endocrinol Metab
August 2023
Article Synopsis
- A meta-analysis was conducted to evaluate the safety and efficacy of rivoglitazone in managing type-2 diabetes (T2DM), as no prior studies had done so.
- The analysis focused on three randomized controlled trials (RCTs) involving 3,591 patients, measuring effects on HbA1c levels, glucose, lipids, and adverse events.
- Results indicated that both standard and high doses of rivoglitazone significantly reduced HbA1c and triglycerides compared to placebo, with no major differences in adverse events when compared to control treatments.
Article Synopsis
- A meta-analysis was conducted to evaluate the effects of luseogliflozin on type-2 diabetes, filling a gap in existing research on this medication.
- The study reviewed 10 randomized controlled trials (RCTs) with 1304 patients, finding significant reductions in HbA1c, fasting glucose, blood pressure, body weight, and triglycerides with luseogliflozin compared to placebo.
- No significant increase in adverse events was observed, suggesting that luseogliflozin is well tolerated and offers benefits similar to other SGLT2 inhibitors, though further cardiovascular outcome studies are needed.