Synthesis and crystal structure of (1,10-phenanthroline-κ ,')[2-(1-pyrazol-1-yl)phenyl-κ , ]iridium(III) hexa-fluorido-phosphate with an unknown number of solvent mol-ecules.

The cationic complex in the title compound, [Ir(CHN)(CHN)]PF, comprises two phenyl-pyrazole (ppz) cyclo-metallating ligands and one 1,10-phenanthroline (phen) ancillary ligand. The asymmetric unit consists of one [Ir(ppz)(phen)] cation and one [PF] counter-ion. The central Ir ion is six-coordinated by two N atoms and two C atoms from the two ppz ligands as well as by two N atoms from the phen ligand within a distorted octa-hedral CN coordination set.

Berberine nanoparticles protects tubular epithelial cells from renal ischemia-reperfusion injury.

Renal ischemia-reperfusion (I/R) injury is one of the most common causes of acute renal failure, the prognosis of which remains poor and there still lacks of effective therapeutics available in the clinic. This study aimed at investigating the effects of Berberine nanoparticles (BBR-NP) on the ischemia-reperfusion injury of renal tubular epithelial cells and underlying the mechanisms. Our results showed that in a rat model of renal I/R injury, BBR and BBR-NP protected renal against injury both functionally (as assessed by serum urea nitrogen and creatinine level) and morphologically (as assessed by HE staining, transmission electron microscopy and TUNEL staining) in a dose-dependent manner, with the effects of BBR-NP superior to BBR alone.

catena-Poly[[tetra-kis-(hexa-methyl-phospho-ramide-κO)bis-(nitrato-κO,O')holmium(III)] [silver(I)-di-μ-sulfido-tungstate(VI)-di-μ-sulfido]].

In the title salt, {[Ho(NO(3))(2)(C(6)H(18)N(3)OP)(4)][AgWS(4)]}(n), the anion forms a W/S/Ag polymeric chain along the a axis. The holmium atom in the cation is coordinated by eight O atoms from two nitrate and four hexa-methyl-phospho-ramide ligands in a distorted square-anti-prismatic geometry. Together with the two nitrate ligands, the complex cation in the title compound is univalent, which leads the anion to be univalent as well.