Publications by authors named "Jusuf Sulaeman Effendi"
Objective: Vitamin D receptor (VDR) exerts anti-cancer properties in a variety of cancers. The purpose of this study was to investigate the expression of VDR in patients with hydatidiform mole (HM) and gestational trophoblastic neoplasia (GTN).
Methods: This is a cross-sectional study involved 61 specimens of HM (n = 37, 60.
Article Synopsis
- Magnesium sulfate (MgSO) treatment in preterm delivery may prevent astrocyte cell death and reduce the inflammatory marker GFAP in umbilical cord blood.
- A study with 68 patients found significant differences in magnesium and GFAP levels between those treated with MgSO and a control group, with higher GFAP in the control group.
- The analysis showed no correlation between maternal magnesium/calcium levels and umbilical GFAP in the treatment group.
Increasing demand for glutaminase (GLS) due to high rates of glutamine metabolism is considered one of the hallmarks of malignancy. In parallel, cancer antigen 125 (CA-125) is a commonly used ovarian tumor marker. This study aimed to compare the roles of GLS and CA-125 in distinguishing between benign and malignant ovarian tumors.
View Article and Find Full Text PDFBACKGROUND Preeclampsia involves an inflammatory response and vascular endothelial dysfunction. In COVID-19, there is also tissue damage and an inflammatory response that stimulates the formation of D-dimers and an increase in the neutrophil-to-lymphocyte ratio (NLR). These 2 parameters have become laboratory tests carried out both in preeclampsia and COVID-19.
View Article and Find Full Text PDFIntroduction: Common bile duct (CBD) injury is the most serious complication of Laparoscopic Cholecystectomy (LapC). Nonetheless, complications of LapC as a treatment for CBD injury are rare in pregnancy. There have been no published case reports regarding complications of CBD injury in gravida patients and their management.
View Article and Find Full Text PDFAim: To investigate the influence of antenatal magnesium sulfate (MgSO4) application on cord blood brain-derived neurotrophic factor (BDNF) levels - the first-line neuroprotection for preventing cerebral palsy in prematurely born infants.
Subjects And Methods: A randomized controlled trial was conducted by observing 72 pregnant women who were divided into three groups: group I (preterm pregnancy with MgSO4), group II (preterm pregnancy without MgSO4), and group III (full-term pregnancy as control group). Groups I and II were selected by block permutation randomization on subjects.