Urinary excretion of renin and angiotensinogen in hypertensive children and adolescents.

Introduction: In recent years hypertension has become an emerging condition in the young population. It has been proposed that the renin-angiotensin system plays an important role in regulation of blood pressure. We assessed whether activation of the intrarenal renin-angiotensin system occurs in hypertensive children and adolescents and what better reflects its activity: urine angiotensinogen (AGT) or urine renin (REN).

Are low birth weight children predisposed to renal loss of carnitine?

The plasma homeostasis of both free and esterified carnitines is mostly regulated by renal tubular reabsorption, which may be disturbed in low birth weight children. The aim of study was to check whether disturbances in excretion of l-carnitine (LC) and its main ester, acetyl-carnitine (ALC), may be the result of renal dysfunction in low birth weight children (LBW). This study included 59 LBW children (2165 g [1490-2440]) and 22 children with normal birth weight as a reference group (3500 g [3275-3650]).

The Possible Impact of Hyperuricemia on Serum Soluble Receptor for Advanced Glycation end Products (sRAGE) Levels in Teenagers: A Case Control Study.

Background: Dietary advanced glycation end products (AGEs) and their interactions with the soluble receptors for AGEs (RAGE) play a crucial role in the pathogenesis of cardiovascular diseases.

Objective: This study was set out to assess, whether there was any association between serum sRAGE level and serum uric acid level in children with hyperuricemia.

Methods: This case-control study involved 53 patients (12 girls, 41 boys) with hyperuricemia (defined as serum uric acid >4.