Publications by authors named "Justine Quintin"
Article Synopsis
- Estradiol signaling helps understand how DNA sequences, chromatin modifications, and genome organization work together to regulate gene expression, particularly through estrogen receptors (ER).
- The study focused on a specific 2-Mb region containing estrogen-sensitive genes in breast cancer cells, highlighting how hormone presence and cohesin proteins affect the 3D structure of DNA to facilitate gene regulation.
- Using advanced techniques, the researchers identified specific ER binding sites (ERBSs) that connect to gene regulation, providing insights into how enhancers work together and the potential redundancy in ERBS functions.
