Publications by authors named "Justine M Chee"
Article Synopsis
- - The study focuses on the MAC spectrum disease, including microphthalmia, anophthalmia, and coloboma, which are eye malformations that can lead to visual impairment in children due to genetic factors, mainly mutations in genes like OTX2 and SOX2, though many cases remain unexplained.
- - Researchers utilized the IMPC database to find 74 unique gene knockout lines in mice that are associated with eye defects, discovering many of these lines had not been previously linked to eye development, ultimately identifying 59 genes of interest.
- - The study highlights the connection between certain genes and protein pathways critical for early eye development, revealing 40 new genes that may play a role in mammalian eye formation,
