Publications by authors named "Justine L M Chow"
Article Synopsis
- Researchers studied lung adenocarcinomas (LUAD) in non-tobacco users to find new genetic drivers of lung cancer, identifying 21 positively selected genes, including 12 that are novel in this context.*
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- One particularly important find was the SHPRH gene, which showed a link between low expression levels and poor survival outcomes in LUAD patients, indicating its potential role as a tumor suppressor.*
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- Reintroducing SHPRH in LUAD cell lines diminished tumor growth and the ability to form colonies, suggesting it’s critical for resistance against DNA damage, which could help predict patient responses to treatments.*
