Publications by authors named "Justine Gonsard"
Article Synopsis
- The COVIT-TRIAL study tested whether a high dose of vitamin D3 given within 72 hours of COVID-19 diagnosis improves 14-day survival rates in at-risk older adults compared to a standard dose.
- Conducted in France across nine medical centers, the trial included patients aged 65 and older with confirmed SARS-CoV-2 infection and specific health risks.
- Of the 1,207 patients evaluated, 254 were eligible and enrolled in the study, which aimed to measure overall mortality as the primary outcome.
Background: With the lack of effective therapy, chemoprevention, and vaccination against SARS-CoV-2, focusing on the immediate repurposing of existing drugs gives hope of curbing the COVID-19 pandemic. A recent unbiased genomics-guided tracing of the SARS-CoV-2 targets in human cells identified vitamin D among the three top-scoring molecules manifesting potential infection mitigation patterns. Growing pre-clinical and epidemiological observational data support this assumption.
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