Normal categorical perception to syllable-like stimuli in long term and in first episode schizophrenia.

Schizophrenia is associated with deficits in language processing that are evident even at first-episode. However, there is debate as to how early in the processing stream the linguistic deficits appear. We measured categorical processing of artificial syllables that varied in voice-onset time (VOT), and how sensory biasing impacts categorical perception.

Reduced late mismatch negativity and auditory sustained potential to rule-based patterns in schizophrenia.

Complex rule-based auditory processing is abnormal in individuals with long-term schizophrenia (SZ), as demonstrated by reduced mismatch negativity (MMN) to deviants in rule-based patterns and reduced auditory sustained potential (ASP) that appears when grouping tones together. Together, this suggests deficits later in the auditory processing hierarchy in Sz. Here, MMN and ASP were elicited by deviations from a complex zig-zag pitch pattern that cannot be predicted by simple linear rules.

Mismatch negativity to pitch pattern deviants in schizophrenia.

Simple mismatch negativity (MMN) to infrequent pitch deviants is impaired in individuals with long-term schizophrenia (Sz). The complex MMN elicited by pattern deviance often manifes is cut from here]->ts later after deviant onset than simple MMN and can ascertain deficits in abstracting relationships between stimuli. Sz exhibit reduced complex MMN, but so far this has only been measured when deviance detection relies on a grouping rule.