End organ effects of high-dose human equivalent methylprednisolone in a spinal cord injury rat model.

Study Design: Interventional study.

Objective: To analyze the histologic effects of high-dose human equivalent methylprednisolone on the pulmonary, cardiac, intestinal, renal, hepatic, and splenic tissues in a spinal cord injury rat model.

Summary Of Background Data: There are numerous investigations of various medical interventions for the treatment of acute spinal cord trauma.