Publications by authors named "Justin Meinert"

Introduction: The routine transfer of mild to moderate traumatic brain injuries (TBIs) to trauma centers with neurosurgical capabilities has recently been re-evaluated. The Brain Injury Guidelines (BIG) were developed to categorize TBI patients into three categories (BIG-1, BIG-2, and BIG-3), each representing a progressively increasing risk of clinical deterioration. This classification system has been previously validated at both level I and level III trauma centers.

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Article Synopsis
  • The study investigates the link between frailty and outcomes in patients undergoing stereotactic radiosurgery (SRS) for brain metastases, revealing that higher frailty scores correlate with worse survival rates.
  • Using a modified frailty index, patients were categorized as pre-frail, frail, or severely frail, with findings showing that frailer patients experienced a significantly reduced overall survival and progression-free survival compared to pre-frail patients.
  • The results indicate that frail patients had a hazard ratio of over 3 for shorter overall survival, emphasizing the need to consider frailty when assessing treatment risks and outcomes in neurosurgery.
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Background: Neuromodulatory implants provide promising alternatives for patients with drug-resistant epilepsy (DRE) in whom resective or ablative surgery is not an option. Responsive neurostimulation (RNS) operates a unique "closed-loop" system of electrocorticography-triggered stimulation for seizure control. A comprehensive review of the current literature would be valuable to guide clinical decision-making regarding RNS.

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Study Design: Systematic review and meta-analysis.

Objectives: Malposition of pedicle screws during instrumentation in the lumbar spine is associated with complications secondary to spinal cord or nerve root injury. Intraoperative triggered electromyographic monitoring (t-EMG) may be used during instrumentation for early detection of malposition.

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Mycobacteriophages Cambiare, FlagStaff, and MOOREtheMARYer are newly isolated phages of Mycobacterium smegmatis mc(2) 155 recovered from soil samples in Pittsburgh, PA. All three genomes are closely related to cluster G mycobacteriophages but differ sufficiently in nucleotide sequence and gene content to warrant division of cluster G into several subclusters.

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