Publications by authors named "Justin K Loden"

Article Synopsis
  • Brown recluse spider envenomation can lead to serious complications like local skin damage and hemolysis, with 40.2% of studied patients experiencing hemolysis after being bitten.
  • A study of 97 patients revealed that younger individuals (mostly under 18) were more prone to hemolysis, and specific symptoms like myalgia and malaise were strong indicators of this condition.
  • Most patients with hemolysis required blood transfusions, and notable complications occurred mainly in those with severe anemia, highlighting the potential severity of brown recluse spider bites.
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Context: Following clonidine ingestion, naloxone is seldom administered as it is considered ineffective in reversing somnolence, bradycardia, or hypotension. However, this conclusion has been based on administration of small doses (2 mg or less) of naloxone. The somnolence is frequently treated with endotracheal intubation (ETI), a procedure with significant morbidity.

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