Synopsis of recent research by authors named "Justin Daho Lee"
- Justin Daho Lee's recent research focuses on the engineering and optimization of genetically encoded fluorescent indicators (GEFIs) using innovative techniques such as machine learning and optogenetics to enhance real-time monitoring of biological activities and redox biology in living cells and tissues.
- His studies have led to the development of advanced sensors, including red fluorescent Genetically Encoded HO Indicators (GEHIs) and a hydRogen perOxide Sensor (oROS), providing tools for the precise monitoring of key oxidants like hydrogen peroxide, critical for understanding various physiological and pathological processes.
- In addition to sensor development, Lee's work also explores the intersection of immunotherapy and cancer biology, particularly through the investigation of CDK4/6 inhibitors in enhancing immune responses in Merkel cell carcinoma, highlighting the multifaceted applications of his research in both basic and clinical sciences.
