Effects of Intravenous Tranexamic Acid During Rhytidectomy: A Randomized, Controlled, Double-Blind Pilot Study.

Background: Tranexamic acid (TXA) is an antifibrinolytic agent shown to decrease intraoperative bleeding, reduce transfusions, and improve outcomes across multiple specialties. Within plastic surgery, initial reports are encouraging but formal studies are lacking.

Objectives: The aim of this study was to determine whether intravenous (IV) TXA has any effect on intraoperative bleeding or postoperative sequelae in patients undergoing a deep-plane facelift.

Use of continuous positive airway pressure after rhinoplasty, septoplasty, and sinus surgery: A survey of current practice patterns.

Objective: To explore current practice patterns in the use of continuous positive airway pressure (CPAP) following nasal or sinus surgery.

Study Design: Cross-sectional survey.

Methods: An electronic 24-question survey was created to evaluate surgeon practice patterns for restarting CPAP after nasal surgery.

Safety of concurrent nasal and oropharyngeal surgery for obstructive sleep apnea.

Objective: This study evaluated for increased complications or risk associated with concurrent nasal and oropharyngeal surgeries to treat patients with obstructive sleep apnea (OSA).

Study Design: Retrospective chart review.

Methods: We performed a retrospective chart review on consecutive patients between 2006 and 2011 who underwent either simultaneous nasal and pharyngeal surgery (group 1) or pharyngeal surgery alone (group 2) to treat OSA.

Severe systemic reaction from calcium hydroxylapatite vocal fold filler.

We describe a severe systemic reaction that occurred following injection augmentation with calcium hydroxylapatite vocal fold filler. The reaction occurred within 30 minutes of the procedure and consisted of diffuse itching, hives, edematous face and eyelids, and voice changes indicating glottic edema. It is classified as a grade 3 systemic reaction.

Laryngeal fracture after coughing.

Nontraumatic laryngeal fractures are exceedingly rare disease entities. Only 3 prior instances have been described in the medical literature (Br Med J 1950;1:1052; Acta Otorrinolaringol Esp 2007;58:73-4; Otolaryngol Head Neck Surg 2012;147:801-2). We present a case of thyroid cartilage fracture and associated phlegmon formation after a vigorous coughing spell in a 47-year-old man.

Mucosal brush biopsy of the oral cavity to detect local, peanut-specific immunoglobulin E.

Background: This study compares the ability of mucosal brush biopsy (MBB) from 2 separate locations in the oral cavity to detect peanut-specific immunoglobulin E (IgE) in patients who report adverse oral cavity reactions when ingesting peanuts.

Methods: Twenty patients who reported a history of oral cavity itching or swelling when ingesting peanuts underwent either MBB of the dorsal tongue (n = 10) or the vestibule (n = 10). Serum testing for total and peanut-specific IgE, using standard immunofluorescent assay, was obtained for all patients.

Axial computed tomography evaluation of the internal nasal valve correlates with clinical valve narrowing and patient complaint.

Background: The objective of this work was to explore the utility of axial computed tomography (CT) imaging to objectively define a narrow internal nasal valve, and compare those findings with clinical examination and patient complaint.

Methods: Retrospective review from a single facial plastic surgery center. We reviewed 40 consecutive patients evaluated for either sinusitis or nasal airway obstruction for which a CT scan was obtained at a single radiology institution.

Radix grafts in cosmetic rhinoplasty: lessons from an 8-year review.

We describe our experience with radix augmentation during cosmetic rhinoplasty over an 8-year period using both autologous and synthetic grafts and provide insight into maximizing success. We discuss various surgical considerations, including patient selection, graft materials, and dealing with complications. We focus on our operative technique and provide patient examples.

Prevalence of over-the-counter and complementary medication use in the otolaryngology preoperative patient: a patient safety initiative.

Objectives/hypothesis: To determine the prevalence of over-the-counter and complementary and alternative medication use in the preoperative otolaryngology patient population.

Study Design: Cross-sectional survey.

Methods: Data were collected from preoperative surveys given to all patients undergoing surgery by a single physician with an academic practice over a 6-month period from March to September 2010.

Laryngeal mucous membrane pemphigoid: a systematic review and pooled-data analysis.

Objectives/hypothesis: To perform a systematic pooled-data analysis of literature data involving laryngeal mucous membrane pemphigoid (MMP).

Study Design: A systematic review and pooled-data analysis.

Methods: We conducted a systematic literature search of MEDLINE, EMBASE, Cochrane Central Register of Clinical Trials, Cochrane Database of Systematic Reviews, clinicaltrials.